Food packaging could be negatively affecting the way in which your digestive tract operates, according to new research by faculty and students at Binghamton University, State University at New York.
"We found that zinc oxide (ZnO) nanoparticles at doses that are relevant to what you might normally eat in a meal or a day can change the way that your intestine absorbs nutrients or your intestinal cell gene and protein expression," said Gretchen Mahler, associate professor of bioengineering.
According to Mahler, these ZnO nanoparticles are present in the lining of certain canned goods for their antimicrobial properties and to prevent staining of sulfur-producing foods. In the study, canned corn, tuna, asparagus and chicken were studied using mass spectrometry to estimate how many particles might be transferred to the food. It was found that the food contained 100 times the daily dietary allowance of zinc. Mahler then looked at the effect the particles had on the digestive tract.
"People have looked at the effects of nanoparticles on intestinal cells before, but they tend to work with really high doses and look for obvious toxicity, like cell death," said Mahler. "We are looking at cell function, which is a much more subtle effect, and looking at nanoparticle doses that are closer to what you might really be exposed to."
"They tend to settle onto the cells representing the gastrointestinal tract and cause remodeling or loss of the microvilli, which are tiny projections on the surface of the intestinal absorptive cells that help to increase the surface area available for absorption," said Mahler. "This loss of surface area tends to result in a decrease in nutrient absorption. Some of the nanoparticles also cause pro-inflammatory signaling at high doses, and this can increase the permeability of the intestinal model.
Read more at: https://phys.org/news/2018-04-food-
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